Semi-Quantitative RT-PCR Method to Estimate Full-Length mRNA Levels of the Multidrug Resistance Gene

Expression levels of P-glycoprotein (P-gp), the transporter encoded by the human multidrug resistance gene (MDR1), may play an important role in drug disposition. The ability to quantitate full-length MDR1 mRNA levels may be predictive of P-gp expression and function. Therefore, a semi-quantitative...

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Bibliographic Details
Main Authors: Z. Yang, E.L. Woodahl, X.-Y. Wang, T. Bui, D.D. Shen, R.J.Y. Ho
Format: Article
Language:English
Published: Taylor & Francis Group 2002-07-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/02331dd03