Human Cytomegalovirus Replication and Infection-Induced Syncytia Formation in Labial, Foreskin, and Fetal Lung Fibroblasts

Human Cytomegalovirus Replication and Infection-Induced Syncytia Formation in Labial, Foreskin, and Fetal Lung Fibroblasts

Only a handful of cell types, including fibroblasts, epithelial, and endothelial cells, can support human cytomegalovirus (CMV) replication in vitro, in striking contrast to the situation in vivo. While the susceptibility of epithelial and endothelial cells to CMV infection is strongly modulated by...

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Bibliographic Details
Main Authors: Alexis Aguiar, Melissa Galinato, Maite’ Bradley Silva, Bryant Toth, Michael A. McVoy, Laura Hertel
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
human cytomegalovirus
fibroblasts
tropism
syncytia
functional genomics
Online Access:https://www.mdpi.com/1999-4915/13/12/2355

Internet

https://www.mdpi.com/1999-4915/13/12/2355

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