Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>

ABSTRACT The cytosolic N-acetylmuramoyl-l-alanine amidase LytA protein of Streptococcus pneumoniae, which is released by bacterial lysis, associates with the cell wall via its choline-binding motif. During exponential growth, LytA accesses its peptidoglycan substrate to cause lysis only when nascent...

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Bibliographic Details
Main Authors: Peter Mellroth, Tatyana Sandalova, Alexey Kikhney, Francisco Vilaplana, Dusan Hesek, Mijoon Lee, Shahriar Mobashery, Staffan Normark, Dmitri Svergun, Birgitta Henriques-Normark, Adnane Achour
Format: Article
Language:English
Published: American Society for Microbiology 2014-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01120-13

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https://journals.asm.org/doi/10.1128/mBio.01120-13

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