The protective effects of empagliflozin on DNA oxidative changes in a model of vascular endothelial and smooth muscle cells damaged by oxidized cholesterol

The protective effects of empagliflozin on DNA oxidative changes in a model of vascular endothelial and smooth muscle cells damaged by oxidized cholesterol

Background: Diabetes patients often suffer chronic vascular complications resulting from endothelial dysfunction, smooth muscle cell (SMC) proliferation, inflammation and disturbed oxidative balance. Empagliflozin is one of three approved sodium-glucose cotransporter 2 (SGLT2) inhibitors for type 2...

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Bibliographic Details
Main Authors: Ewelina Woźniak, Magdalena Świstek, Marlena Broncel, Bożena Bukowska, Paulina Gorzelak-Pabiś
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
DNA bases
DNA oxidative damage
Empagliflozin
Vascular endothelial damage
Oxidized cholesterol
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223018632

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http://www.sciencedirect.com/science/article/pii/S0753332223018632

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