The Immunomodulatory Effect and Clinical Efficacy of Daratumumab in a Patient With Cold Agglutinin Disease

The Immunomodulatory Effect and Clinical Efficacy of Daratumumab in a Patient With Cold Agglutinin Disease

Daratumumab is a monoclonal antibody directed against the transmembrane glycoprotein CD38 expressed on plasma cells and lymphoplasmocytes, with a proven efficacy in multiple myeloma. Here we show its clinical efficacy in a patient with cold agglutinin disease (CAD) relapsed after multiple lines of t...

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Bibliographic Details
Main Authors: Anna Zaninoni, Juri A. Giannotta, Anna Gallì, Rosangela Artuso, Paola Bianchi, Luca Malcovati, Wilma Barcellini, Bruno Fattizzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
cold agglutinin disease
daratumumab
cytokines
autoimmune diseases
anti-CD38 MoAb
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.649441/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.649441/full

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