Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence of few genomic differences between Mtb isolates might indicate TB cases are the result of recent transmission. However, the variable an...

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Bibliographic Details
Main Authors: Kristin N. Nelson, Sarah Talarico, Shameer Poonja, Clinton J. McDaniel, Martin Cilnis, Alicia H. Chang, Kala Raz, Wendy S. Noboa, Lauren Cowan, Tambi Shaw, James Posey, Benjamin J. Silk
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Public Health
Subjects:
tuberculosis—epidemiology
prevention and control
genomic sequencing
tuberculosis transmission
public health practice
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2021.790544/full

Internet

https://www.frontiersin.org/articles/10.3389/fpubh.2021.790544/full

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