Synergistic Encapsulation of Paclitaxel and Sorafenib by Methoxy Poly(Ethylene Glycol)-<i>b</i>-Poly(Caprolactone) Polymeric Micelles for Ovarian Cancer Therapy

Synergistic Encapsulation of Paclitaxel and Sorafenib by Methoxy Poly(Ethylene Glycol)-<i>b</i>-Poly(Caprolactone) Polymeric Micelles for Ovarian Cancer Therapy

Ovarian cancer has a high mortality rate due to difficult detection at an early stage. It is necessary to develop a novel anticancer treatment that demonstrates improved efficacy while reducing toxicity. Here, using the freeze-drying method, micelles encapsulating paclitaxel (PTX) and sorafenib (SRF...

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Bibliographic Details
Main Authors: Chae Eun Jin, Moon Sup Yoon, Min Jeong Jo, Seo Yeon Kim, Jae Min Lee, Su Jeong Kang, Chun-Woong Park, Jin-Seok Kim, Dae Hwan Shin
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
ovarian cancer
paclitaxel
sorafenib
combination therapy
mPEG-<i>b</i>-PCL
micelle
Online Access:https://www.mdpi.com/1999-4923/15/4/1206

Internet

https://www.mdpi.com/1999-4923/15/4/1206

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