Tokishakuyakusan ameliorates spatial memory deficits induced by ovariectomy combined with β-amyloid in rats

Previously, we reported that ovariectomy (OVX) combined with β-amyloid peptide (Aβ) impaired spatial memory by decreasing extracellular acetylcholine (ACh) levels in the dorsal hippocampus. Here, we investigated the effect of tokishakuyakusan (TSS), a Kampo medicine, on the impairment of spatial mem...

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Bibliographic Details
Main Authors: Nobuaki Egashira, Yuki Akiyoshi, Hikari Iba, Takashi Arai, Izzettin Hatip-Al-Khatib, Kenichi Mishima, Katsunori Iwasaki
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318300173