Protective Effect of Knee Postoperative Fluid on Oxidative-Induced Damage in Human Knee Articular Chondrocytes

Protective Effect of Knee Postoperative Fluid on Oxidative-Induced Damage in Human Knee Articular Chondrocytes

The oxidative-stress-elicited deterioration of chondrocyte function is the initial stage of changes leading to the disruption of cartilage homeostasis. These changes entail a series of catabolic damages mediated by proinflammatory cytokines, MMPs, and aggrecanases, which increase ROS generation. Suc...

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Bibliographic Details
Main Authors: Roberta Giordo, Smitha Tulasigeri Totiger, Gianfilippo Caggiari, Annalisa Cossu, Andrea Fabio Manunta, Anna Maria Posadino, Gianfranco Pintus
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Antioxidants
Subjects:
reactive oxygen species
osteoarthritis
chondrocytes
growth factors
post-operation knee fluid
Online Access:https://www.mdpi.com/2076-3921/13/2/188

Internet

https://www.mdpi.com/2076-3921/13/2/188

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