Potential Mechanisms of the Impact of Hepatocyte Growth Factor Gene-Modified Tendon Stem Cells on Tendon Healing

Potential Mechanisms of the Impact of Hepatocyte Growth Factor Gene-Modified Tendon Stem Cells on Tendon Healing

The therapeutic impact of stem cells is potentially largely attributable to secretion of exosomes and soluble factors. The present study evaluates the impact of hepatocyte growth factor (HGF)–expressing tendon stem cells (TSCs) on tendon healing in a rat model. Patellar tendon TSCs were isolated and...

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Bibliographic Details
Main Authors: Mingzhao Zhang, Hengchen Liu, Manyu Shi, Tingting Zhang, Wenjun Lu, Shulong Yang, Qingbo Cui, Zhaozhu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tendon stem cells
hepatocyte growth factor
inflammation
fibrosis
tendon healing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.659389/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.659389/full

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