Role of Syndecan-4 in the Inhibition of Articular Cartilage Degeneration in Osteoarthritis

Role of Syndecan-4 in the Inhibition of Articular Cartilage Degeneration in Osteoarthritis

Despite its widespread existence, there are relatively few drugs that can inhibit the progression of osteoarthritis (OA). Syndecan-4 (SDC4) is a transmembrane heparan sulfate proteoglycan that modulates cellular interactions with the extracellular matrix. Upregulated SDC4 expression in articular car...

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Bibliographic Details
Main Authors: Yoshio Hattori, Masahiro Hasegawa, Takahiro Iino, Kyoko Imanaka-Yoshida, Akihiro Sudo
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
articular cartilage
osteoarthritis
syndecan-4
heparan sulfate proteoglycan
Online Access:https://www.mdpi.com/2227-9059/11/8/2257

Internet

https://www.mdpi.com/2227-9059/11/8/2257

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