Inhibition of host 5-lipoxygenase reduces overexuberant inflammatory responses and mortality associated with Cryptococcus meningoencephalitis

Inhibition of host 5-lipoxygenase reduces overexuberant inflammatory responses and mortality associated with Cryptococcus meningoencephalitis

ABSTRACT Cryptococcosis, caused by fungi of the genus Cryptococcus, manifests in a broad range of clinical presentations, including severe pneumonia and disease of the central nervous system (CNS) and other tissues (bone and skin). Immune deficiency or development of overexuberant inflammatory respo...

詳細記述

書誌詳細
主要な著者: Natalia Castro-Lopez, Althea Campuzano, Elysa Mdalel, Difernando Vanegas, Ashok Chaturvedi, Phung Nguyen, Mark Pulse, Astrid E. Cardona, Floyd L. Wormley
フォーマット: 論文
言語:English
出版事項: American Society for Microbiology 2024-09-01
シリーズ:mBio
主題:
Cryptococcus
Cryptococcosis
5-lipoxygenase
meningitis
meningoencephalitis
Cryptococcus neoformans
オンライン･アクセス:https://journals.asm.org/doi/10.1128/mbio.01483-24

インターネット

https://journals.asm.org/doi/10.1128/mbio.01483-24

類似資料