Inhibition of host 5-lipoxygenase reduces overexuberant inflammatory responses and mortality associated with Cryptococcus meningoencephalitis

Inhibition of host 5-lipoxygenase reduces overexuberant inflammatory responses and mortality associated with Cryptococcus meningoencephalitis

ABSTRACT Cryptococcosis, caused by fungi of the genus Cryptococcus, manifests in a broad range of clinical presentations, including severe pneumonia and disease of the central nervous system (CNS) and other tissues (bone and skin). Immune deficiency or development of overexuberant inflammatory respo...

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Những tác giả chính: Natalia Castro-Lopez, Althea Campuzano, Elysa Mdalel, Difernando Vanegas, Ashok Chaturvedi, Phung Nguyen, Mark Pulse, Astrid E. Cardona, Floyd L. Wormley
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: American Society for Microbiology 2024-09-01
Loạt:mBio
Những chủ đề:
Cryptococcus
Cryptococcosis
5-lipoxygenase
meningitis
meningoencephalitis
Cryptococcus neoformans
Truy cập trực tuyến:https://journals.asm.org/doi/10.1128/mbio.01483-24

Internet

https://journals.asm.org/doi/10.1128/mbio.01483-24

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