An interferon-integrated mucosal vaccine provides pan-sarbecovirus protection in small animal models

Abstract A pan-sarbecovirus or pan-betacoronavirus vaccine that can prevent current and potential future beta-coronavirus infections is important for fighting possible future pandemics. Here, we report a mucosal vaccine that cross-protects small animal models from sarbecoviruses including SARS-CoV-1...

Full description

Bibliographic Details
Main Authors: Chun-Kit Yuen, Wan-Man Wong, Long-Fung Mak, Joy-Yan Lam, Lok-Yi Cheung, Derek Tsz-Yin Cheung, Yau-Yee Ng, Andrew Chak-Yiu Lee, Nanshan Zhong, Kwok-Yung Yuen, Kin-Hang Kok
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42349-5