Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals

Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals

Summary: The NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome has been involved in the pathogenesis of various chronic liver diseases. However, its role in hepatitis B virus (HBV)-associated hepatitis remains unknown. Here we demonstrate the synergistic effect of HBV with potent...

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Bibliographic Details
Main Authors: Jingxue Wang, Qian Liu, Yiwen Zhou, Chunhao Cao, Penghui Chen, Gang Meng, Ji Zhang, Xiaojuan Xin, Guangyu Huang, Yuzhang Wu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Molecular biology
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223028006

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http://www.sciencedirect.com/science/article/pii/S2589004223028006

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