Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson’s disease

Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson’s disease

Background: Parkinson’s disease is associated with severe nigro-striatal dopamine depletion, leading to motor dysfunction and altered reward processing. We previously showed that drug-naïve patients with Parkinson’s disease had a consistent attenuation of reward signalling in the mesolimbic and meso...

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Bibliographic Details
Main Authors: Joyce P.M. van der Vegt, Oliver J. Hulme, Kristoffer H. Madsen, Carsten Buhmann, Bastiaan R. Bloem, Alexander Münchau, Rick C. Helmich, Hartwig R. Siebner
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
fMRI
Reward
Mesolimbic system
Parkinson's disease
Drug-naïve, dopamine-agonist
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220301996

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http://www.sciencedirect.com/science/article/pii/S2213158220301996

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