A Novel <italic toggle="yes">Shigella</italic> Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge

A Novel <italic toggle="yes">Shigella</italic> Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge

ABSTRACT Shigella spp. are a major cause of diarrhea and dysentery in children under 5 years old in the developing world. The development of an effective vaccine remains a public health priority, necessitating improved understanding of immune responses to Shigella and identification of protective an...

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Bibliographic Details
Main Authors: Esther Ndungo, Arlo Randall, Tracy H. Hazen, Dane A. Kania, Krista Trappl-Kimmons, Xiaowu Liang, Eileen M. Barry, Karen L. Kotloff, Subhra Chakraborty, Sachin Mani, David A. Rasko, Marcela F. Pasetti
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
Shigella
antibodies
proteome microarray
vaccines
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00260-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00260-18

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