Targeting Translation and the Cell Cycle Inversely Affects CTC Metabolism but Not Metastasis
Melanoma brain metastasis (MBM) is significantly associated with poor prognosis and is diagnosed in 80% of patients at autopsy. Circulating tumor cells (CTCs) are “seeds” of metastasis and the smallest functional units of cancer. Our multilevel approach has previously identified a CTC RPL/RPS gene s...
Main Authors: | Tetiana Y. Bowley, Seth D. Merkley, Irina V. Lagutina, Mireya C. Ortiz, Margaret Lee, Bernard Tawfik, Dario Marchetti |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/21/5263 |
Similar Items
-
Analysis of Circulating Tumour Cells in Early-Stage Uveal Melanoma: Evaluation of Tumour Marker Expression to Increase Capture
by: Aaron B. Beasley, et al.
Published: (2021-11-01) -
Detection of Circulating Tumor Cells (CTCs) in Malignant Pleural Mesothelioma (MPM) with the “Universal” CTC-Chip and An Anti-Podoplanin Antibody NZ-1.2
by: Taiji Kuwata, et al.
Published: (2020-04-01) -
Harnessing NK Cells to Control Metastasis
by: Xuewen Deng, et al.
Published: (2022-11-01) -
Analysis of a Real-World Cohort of Metastatic Breast Cancer Patients Shows Circulating Tumor Cell Clusters (CTC-clusters) as Predictors of Patient Outcomes
by: Clotilde Costa, et al.
Published: (2020-04-01) -
Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring
by: Paula Kamińska, et al.
Published: (2021-09-01)