High percentage of blood-based T-cell receptor gamma V9-JP recombinations associated with amyotrophic lateral sclerosis: extensive retention of the JP KKIK amino acid motif

Exome and RNAseq files prepared from blood samples can be mined for adaptive immune receptor recombinations and thus for the complementarity determining region-3 (CDR3) amino acid (AA) sequences, important for antigen binding. In this report, the T-cell receptor gamma (TRG) recombinations were mined...

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Bibliographic Details
Main Authors: George Blanck, Taha I. Huda, Konrad J. Cios, George Angelakakis, Joanna J. Song
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-12-01
Series:Exploration of Immunology
Subjects:
Online Access:https://www.explorationpub.com/Journals/ei/Article/1003124