Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to DamageSummary

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to DamageSummary

Background & Aims: The colonic epithelium requires continuous renewal by crypt resident intestinal stem cells (ISCs) and transit-amplifying (TA) cells to maintain barrier integrity, especially after inflammatory damage. The diet of high-income countries contains increasing amounts of sugar,...

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Bibliographic Details
Main Authors: Ansen H.P. Burr, Junyi Ji, Kadir Ozler, Heather L. Mentrup, Onur Eskiocak, Brian Yueh, Rachel Cumberland, Ashley V. Menk, Natalie Rittenhouse, Chris W. Marshall, Pailin Chiaranunt, Xiaoyi Zhang, Lauren Mullinax, Abigail Overacre-Delgoffe, Vaughn S. Cooper, Amanda C. Poholek, Greg M. Delgoffe, Kevin P. Mollen, Semir Beyaz, Timothy W. Hand
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Stemness
Renewal
DCA
Mitochondria
Colitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23000632

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http://www.sciencedirect.com/science/article/pii/S2352345X23000632

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