Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms
(1) Background. The endocannabinoid (eCB) system, which regulates physiological and cognitive processes, presents a promising therapeutic target for treating HIV-associated neurocognitive disorders (HAND). Here we examine whether upregulating eCB tone has potential protective effects against HIV-1 T...
Main Authors: | Changqing Xu, Barkha J. Yadav-Samudrala, Callie Xu, Bhupendra Nath, Twisha Mistry, Wei Jiang, Micah J. Niphakis, Benjamin F. Cravatt, Somnath Mukhopadhyay, Aron H. Lichtman, Bogna M. Ignatowska-Jankowska, Sylvia Fitting |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/5/857 |
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