A synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance
Abstract The lack of new drugs that are effective against antibiotic-resistant bacteria has caused increasing concern in global public health. Based on this study, we report development of a modified antimicrobial drug through structure-based drug design (SBDD) and modular synthesis. The optimal mod...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-50453-3 |