Chemical Synthesis of the PAX Protein Inhibitor EG1 and Its Ability to Slow the Growth of Human Colorectal Carcinoma Cells

Chemical Synthesis of the PAX Protein Inhibitor EG1 and Its Ability to Slow the Growth of Human Colorectal Carcinoma Cells

Colorectal cancer is primarily a disease of the developed world. The incidence rate has continued to increase over time, reflecting both demographic and lifestyle changes, which have resulted in genomic and epigenomic modifications. Many of the epigenetic modifications occur in genes known to be clo...

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Bibliographic Details
Main Authors: Lorissa McDougall, Jui Thiang Brian Kueh, Jake Ward, Joel D. A. Tyndall, Adele G. Woolley, Sunali Mehta, Cherie Stayner, David S. Larsen, Michael R. Eccles
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
paired box
PAX
colorectal carcinoma
EG1
treatment
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.709540/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.709540/full

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