Maternal Obesity Programs the Premature Aging of Rat Offspring Liver Mitochondrial Electron Transport Chain Genes in a Sex-Dependent Manner

Maternal Obesity Programs the Premature Aging of Rat Offspring Liver Mitochondrial Electron Transport Chain Genes in a Sex-Dependent Manner

We investigated whether maternal obesity affects the hepatic mitochondrial electron transport chain (ETC), sirtuins, and antioxidant enzymes in young (110 postnatal days (PND)) and old (650PND) male and female offspring in a sex- and age-related manner. Female Wistar rats ate a control (C) or high-f...

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Bibliographic Details
Main Authors: Consuelo Lomas-Soria, Guadalupe L. Rodríguez-González, Carlos A. Ibáñez, Luis A. Reyes-Castro, Peter W. Nathanielsz, Elena Zambrano
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biology
Subjects:
maternal obesity
aging
RNA-seq
liver
mitochondria
oxidative phosphorylation
Online Access:https://www.mdpi.com/2079-7737/12/9/1166

Internet

https://www.mdpi.com/2079-7737/12/9/1166

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