Identification of Rab41/6d effectors provides an explanation for the differential effects of Rab41/6d and Rab6a/a' on Golgi organization

Identification of Rab41/6d effectors provides an explanation for the differential effects of Rab41/6d and Rab6a/a' on Golgi organization

Unexpectedly, members of the Rab VI subfamily exhibit considerable variation in their effects on Golgi organization and trafficking. By fluorescence microscopy, neither depletion nor overexpression of the GDP-locked form of Rab6a/a’, the first trans Golgi-associated Rab protein discovered, affects...

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Bibliographic Details
Main Authors: Shijie eLiu, Waqar eMajeed, Tetyana eKudlyk, Vladimir eLupashin, Brian eStorrie
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
effector
Syntaxin 8
Golgi organization
Rab41/6d
dynactin 6
Rab6a/a’
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00013/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00013/full

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