Lack of impact of OCTN1 gene polymorphisms on clinical outcomes of gabapentinoids in Pakistani patients with neuropathic pain

<h4>Background and objective</h4> Gabapentinoids are the first-line drugs for neuropathic pain. These drugs are the substrate of organic cation transporter (OCTN1) for renal excretion and absorption across the intestinal epithelium. Gabapentinoids exhibit wide interindividual variability...

Full description

Bibliographic Details
Main Authors: Abida Shaheen, Syed Mahboob Alam, Fahad Azam, Salman Ahmad Saleem, Moosa Khan, Syed Saud Hasan, Afrose Liaquat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106170/?tool=EBI