Association of ACE2 Polymorphisms and Derived Haplotypes With Obesity and Hyperlipidemia in Female Spanish Adolescents

Association of ACE2 Polymorphisms and Derived Haplotypes With Obesity and Hyperlipidemia in Female Spanish Adolescents

BackgroundIn the cardiovascular (CV) system, overactivation of the angiotensin converting enzyme (ACE) may trigger deleterious responses derived from angiotensin (Ang)-II, which can be attenuated by stimulation of ACE2 and subsequent Ang-(1-7) metabolite. However, ACE2 exhibits a high degree of gene...

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Bibliographic Details
Main Authors: Jairo Lumpuy-Castillo, Claudia Vales-Villamarín, Ignacio Mahíllo-Fernández, Iris Pérez-Nadador, Leandro Soriano-Guillén, Oscar Lorenzo, Carmen Garcés
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
ACE2
SNP
haplotype
cardiovascular
obesity
hyperlipidemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.888830/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.888830/full

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