Uncovering novel MHC alleles from RNA-Seq data: expanding the spectrum of MHC class I alleles in sheep

Abstract Background Major histocompatibility complex (MHC) class I glycoproteins present selected peptides or antigens to CD8 + T cells that control the cytotoxic immune response. The MHC class I genes are among the most polymorphic loci in the vertebrate genome, with more than twenty thousand allel...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Johannes Buitkamp
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BMC 2023-01-01
Cyfres:BMC Genomic Data
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s12863-022-01102-5