Bioconversion of 4-hydroxyestradiol by extradiol ring-cleavage dioxygenases from Novosphingobium sp. PP1Y

Abstract Livestock breeding activities and pharmaceutical wastes lead to considerable accumulation of steroid hormones and estrogens in wastewaters. Here estrogens act as pro-cancerogenic agents and endocrine disruptors interfering with the sexual development of aquatic animals and having toxic effe...

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Bibliographic Details
Main Authors: Francesca Mensitieri, Andrea Bosso, Fabrizio Dal Piaz, Bruno Charlier, Eugenio Notomista, Viviana Izzo, Valeria Cafaro
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28908-2