Notch1 signaling is limited in healthy mature kidneys in vivo

Notch1 signaling is limited in healthy mature kidneys in vivo

Abstract Objective A Delta-Notch signaling component, Notch1, is involved in the normal development and multiple disorders of the kidney. Although the increase in Notch1 signaling is crucial to these pathogeneses, the basal signaling level in ‘healthy’ mature kidneys is still unclear. To address thi...

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Bibliographic Details
Main Authors: Ryosuke Sugiura, Takahiro Nakayama, Teppei Nishino, Naoto Sambe, Freddy Radtke, Masaharu Yoshihara, Satoru Takahashi
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Research Notes
Subjects:
Cre/loxP system
Delta-Notch signaling pathway
Disease model
Gal4/UAS system
Transgenic mouse
Online Access:https://doi.org/10.1186/s13104-023-06326-x

Internet

https://doi.org/10.1186/s13104-023-06326-x

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