SDF-1α mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer.

SDF-1α mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer.

Increased growth of residual tumors in the proximity of acute surgical wounds has been reported; however, the mechanisms of wound-promoted tumor growth remain unknown. Here, we used a syngeneic, orthotopic mouse model of breast cancer to study mechanisms of wound-promoted tumor growth. Our results d...

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Bibliographic Details
Main Authors: Christina H Stuelten, Frances N Cervoni-Curet, Johanna I Busch, Emily Sutton, Joshua D Webster, Sandra L Kavalukas, Lalage M Wakefield, Adrian Barbul, John E Niederhuber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3623916?pdf=render

Internet

http://europepmc.org/articles/PMC3623916?pdf=render

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