Vincristine induces somatic segregation, via mitotic crossing-over, in diploid cells of Aspergillus nidulans
Vincristine is an alkaloid widely used as an antineoplastic agent. In eukaryotic cells the drug causes blockage in the G2 phase of the cell cycle and an increase in the frequency of sister chromatid exchanges. Due to the fact that germinating Aspergillus nidulans cells spend most of their cycle in G...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2002-01-01
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| Series: | Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000100006 |