Endothelial Indoleamine-2,3-Dioxygenase-1 is not Critically Involved in Regulating Antitumor Immunity in the Central Nervous System

The vascular niche of malignant gliomas is a key compartment that shapes the immunosuppressive brain tumor microenvironment (TME). The blood-brain-barrier (BBB) consisting of specialized endothelial cells (ECs) and perivascular cells forms a tight anatomical and functional barrier critically control...

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Bibliographic Details
Main Authors: AP Abu Hejleh, K Huck, K Jähne, CL Tan, TV Lanz, L Epping, JK Sonner, SG Meuth, A Henneberg, CA Opitz, C Herold-Mende, F Sahm, M Platten, K Sahm
Format: Article
Language:English
Published: SAGE Publishing 2023-02-01
Series:International Journal of Tryptophan Research
Online Access:https://doi.org/10.1177/11786469231153111