Effect of volume flows on the viability of MSCs during injection through a cannula

Introduction: Clinical trials currently evaluate the use of mesenchymal stem cells (MSCs) for the treatment of non-union bone fractures. The stem cells are injected directly into the non-union area of a bone via a cannula. During this injection process, pressure and shear forces affect the MSCs whic...

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Bibliographic Details
Main Authors: Nießen Lina, Facchinetti Giulia, Elsner Till, Wendlandt Robert, Gemoll Timo, Habermann Jens K., Schulz Arndt-Peter
Format: Article
Language:English
Published: De Gruyter 2021-10-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2021-2069