Nanopore sequencing of PCR products enables multicopy gene family reconstruction

Nanopore sequencing of PCR products enables multicopy gene family reconstruction

The importance of gene amplifications in evolution is more and more recognized. Yet, tools to study multi-copy gene families are still scarce, and many such families are overlooked using common sequencing methods. Haplotype reconstruction is even harder for polymorphic multi-copy gene families. Here...

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Bibliographic Details
Main Authors: Alice Namias, Kristoffer Sahlin, Patrick Makoundou, Iago Bonnici, Mathieu Sicard, Khalid Belkhir, Mylène Weill
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Multi-copy genes
Nanopore sequencing
PCR recombination
Wolbachia
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023002477

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http://www.sciencedirect.com/science/article/pii/S2001037023002477

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