Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus

Antibiotic resistance in Staphylococcus aureus is associated with reduced neutrophil recruitment. Here, Payne et al. link formylated peptides, which act as chemoattractants for neutrophils, with the antibiotic vancomycin and show that these hybrid compounds improve clearance of S. aureus by neutroph...

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Bibliographic Details
Main Authors: Jennifer A. E. Payne, Julien Tailhades, Felix Ellett, Xenia Kostoulias, Alex J. Fulcher, Ting Fu, Ryan Leung, Stephanie Louch, Amy Tran, Severin A. Weber, Ralf B. Schittenhelm, Graham J. Lieschke, Chengxue Helena Qin, Daniel Irima, Anton Y. Peleg, Max J. Cryle
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26244-5