RIP140-Mediated NF-κB Inflammatory Pathway Promotes Metabolic Dysregulation in Retinal Pigment Epithelium Cells

Metabolic dysregulation of the retinal pigment epithelium (RPE) has been implicated in age-related macular degeneration (AMD). However, the molecular regulation of RPE metabolism remains unclear. RIP140 is known to affect oxidative metabolism and mitochondrial biogenesis by negatively controlling mi...

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Bibliographic Details
Main Authors: Zeli Guo, Yuli Shen, Jianwen Zhong, Zhuoyun Li, Qi Guo, Xiangchao Yao, Yandong Wang, Wenyu Wu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/44/11/393