The dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in Tanzania.

Naturally acquired immune responses against sexual stages of P. falciparum can reduce the transmission of malaria from humans to mosquitoes. These antigens are candidate transmission-blocking vaccines but little is known about the acquisition of sexual stage immunity after exposure to gametocytes, o...

Full description

Bibliographic Details
Main Authors: Teun Bousema, Will Roeffen, Hinta Meijerink, Harry Mwerinde, Steve Mwakalinga, Geert-Jan van Gemert, Marga van de Vegte-Bolmer, Frank Mosha, Geoffrey Targett, Eleanor M Riley, Robert Sauerwein, Chris Drakeley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2993929?pdf=render