S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity

Abstract Background Lung cancer is one of the most frequently diagnosed cancers characterized by high mortality, metastatic potential, and recurrence. Deregulated gene expression of lung cancer, likewise in many other solid tumors, accounts for their cell heterogeneity and plasticity. S-adenosylhomo...

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Main Authors: Melina Muñoz-Bernart, Nicolás Budnik, Araceli Castro, Malena Manzi, María Eugenia Monge, Julieta Pioli, Sebastián Defranchi, Gustavo Parrilla, Juan Pablo Santilli, Kevin Davies, Joaquín M. Espinosa, Ken Kobayashi, Carlos Vigliano, Carolina Perez-Castro
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Biology Direct
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Online Access:https://doi.org/10.1186/s13062-023-00364-y