Biomimetic platelet nanoparticles encapsulated with proteasome inhibitor bortezomib for multiple myeloma treatment

The discovery of bortezomib (BTZ) has been a major clinical breakthrough for multiple myeloma (MM) treatment. However, its clinical application is restricted to a low tumor-targeting ability, fast clearance, and treatment-related toxicity. Here, we report a targeting strategy of MM by poly(lactic-co...

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Bibliographic Details
Main Authors: Guangtao Gao, Yong Xu, Jingjing Gan, Xinya Cao, Xiaoqing Dong, Mengkun Fang, Ying Du, Peipei Xu, Junyi Che, Bing Chen
Format: Article
Language:English
Published: AIP Publishing LLC 2023-12-01
Series:APL Materials
Online Access:http://dx.doi.org/10.1063/5.0180225