Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning

Sugar porters (SPs) represent the largest group of secondary-active transporters. Some members, such as the glucose transporters (GLUTs), are well known for their role in maintaining blood glucose homeostasis in mammals, with their expression upregulated in many types of cancers. Because only a few...

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Bibliographic Details
Main Authors: Darko Mitrovic, Sarah E McComas, Claudia Alleva, Marta Bonaccorsi, David Drew, Lucie Delemotte
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/84805