Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning
Sugar porters (SPs) represent the largest group of secondary-active transporters. Some members, such as the glucose transporters (GLUTs), are well known for their role in maintaining blood glucose homeostasis in mammals, with their expression upregulated in many types of cancers. Because only a few...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-07-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/84805 |