The modified 2VO ischemia protocol causes cognitive impairment similar to that induced by the standard method, but with a better survival rate
Permanent bilateral occlusion of the common carotid arteries (2VO) in the rat has been established as a valid experimental model to investigate the effects of chronic cerebral hypoperfusion on cognitive function and neurodegenerative processes. Our aim was to compare the cognitive and morphological...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2010-12-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200007 |