Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities
Gastric cancer (GC), one of the most common malignancies worldwide, is a heterogeneous disease developing from the accumulation of genetic and epigenetic changes. One of the most critical epigenetic alterations in GC is DNA and histone methylation, which affects multiple processes in the cell nucleu...
Main Authors: | Katia De Marco, Paola Sanese, Cristiano Simone, Valentina Grossi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/20/4976 |
Similar Items
-
Tackling malignant melanoma epigenetically: histone lysine methylation
by: Elias Orouji, et al.
Published: (2018-11-01) -
Role of Histone Methylation in Maintenance of Genome Integrity
by: Arjamand Mushtaq, et al.
Published: (2021-06-01) -
Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors
by: Melanie A. Whitmore, et al.
Published: (2022-04-01) -
Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke
by: Svetlana Sharifulina, et al.
Published: (2021-11-01) -
DNA or Protein Methylation-Dependent Regulation of Activator Protein-1 Function
by: Eunji Kim, et al.
Published: (2021-02-01)