Mechanisms of Cancer Induction by Tobacco-Specific NNK and NNN

Tobacco use is a major public health problem worldwide. Tobacco-related cancers cause millions of deaths annually. Although several tobacco agents play a role in the development of tumors, the potent effects of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN)...

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Bibliographic Details
Main Authors: Jiaping Xue, Suping Yang, Seyha Seng
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/6/2/1138