Network-driven analysis of human–Plasmodium falciparum interactome: processes for malaria drug discovery and extracting in silico targets

Abstract Background The emergence and spread of malaria drug resistance have resulted in the need to understand disease mechanisms and importantly identify essential targets and potential drug candidates. Malaria infection involves the complex interaction between the host and pathogen, thus, functio...

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Bibliographic Details
Main Authors: Francis E. Agamah, Delesa Damena, Michelle Skelton, Anita Ghansah, Gaston K. Mazandu, Emile R. Chimusa
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Malaria Journal
Subjects:
Online Access:https://doi.org/10.1186/s12936-021-03955-0