S100A14: A novel negative regulator of cancer stemness and immune evasion by inhibiting STAT3‐mediated programmed death‐ligand 1 expression in colorectal cancer

S100A14: A novel negative regulator of cancer stemness and immune evasion by inhibiting STAT3‐mediated programmed death‐ligand 1 expression in colorectal cancer

Abstract Background Programmed death‐ligand 1 (PD‐L1) has functional roles in cancer stem‐like cell (CSC) phenotypes and chemoresistance besides immune evasion. Chemotherapy is a common treatment choice for colorectal cancer (CRC) patients; however, chemoresistance limits its effectiveness of treatm...

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Bibliographic Details
Main Authors: Hye‐Young Min, Jaebeom Cho, Jeong Yeon Sim, Hye‐Jin Boo, Ji‐Sun Lee, Seon‐Boon Lee, Young‐Jin Lee, Sung Joo Kim, Kyu‐Pyo Kim, In‐Ja Park, Seung‐Mo Hong, Xue‐Li Zhang, Zhi‐Gang Zhang, Rang‐Woon Park, Ho‐Young Lee
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical and Translational Medicine
Subjects:
cancer stem‐like cells
colorectal cancer
PD‐L1
STAT3
S100A14
Online Access:https://doi.org/10.1002/ctm2.986

Internet

https://doi.org/10.1002/ctm2.986

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