Assessing the safety of lipid-modifying medications among Chinese adolescents: a drug-target Mendelian randomization study

Assessing the safety of lipid-modifying medications among Chinese adolescents: a drug-target Mendelian randomization study

Abstract Background With increasing hypercholesterolemia prevalence in East Asian adolescents, pharmacologic interventions (e.g., HMGCR inhibitors (statins) and PCSK9 inhibitors) may have to be considered although their longer-term safety in the general adolescent population is unclear. This study a...

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Bibliographic Details
Main Authors: Shan Luo, Hugh Simon Lam, Yap Hang Chan, Clara Sze Man Tang, Baoting He, Man Ki Kwok, Gabriel M. Leung, C Mary Schooling, Shiu Lun Au Yeung
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Medicine
Subjects:
HMGCR inhibitors
PCSK9 inhibitors
Safety
Adolescents
Drug-target Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-023-03115-y

Internet

https://doi.org/10.1186/s12916-023-03115-y

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