A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data.

A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data.

BACKGROUND:How transcription factors (TFs) interact with cis-regulatory sequences and interact with each other is a fundamental, but not well understood, aspect of gene regulation. METHODOLOGY/PRINCIPAL FINDINGS:We present a computational method to address this question, relying on the established b...

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Bibliographic Details
Main Authors: Xin He, Chieh-Chun Chen, Feng Hong, Fang Fang, Saurabh Sinha, Huck-Hui Ng, Sheng Zhong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2780727?pdf=render

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http://europepmc.org/articles/PMC2780727?pdf=render

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