Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer

Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells. However, the functional roles and regulated mechanisms of PDHA1 in multiple cancers are largely unknown. The Cancer Geno...

Full description

Bibliographic Details
Main Authors: Langmei Deng, Anqi Jiang, Hanqing Zeng, Xiaoji Peng, Liying Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.947372/full