CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

BACKGROUND: CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD). The increasing use of allogeneic hematopoietic stem cell transplanta...

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Bibliographic Details
Main Authors: Hiroshi Takahashi, Kazuhiko Ikeda, Kazuei Ogawa, Syunnichi Saito, Alain M Ngoma, Yumiko Mashimo, Koki Ueda, Miki Furukawa, Akiko Shichishima-Nakamura, Hiroshi Ohkawara, Kenneth E Nollet, Hitoshi Ohto, Yasuchika Takeishi
Format: Article
Language:English
Published: BMC 2015-01-01
Series:Biological Research
Subjects:
Regulatory T cells
Allogeneic hematopoietic stem cell transplantation
Thymus
Graft-versus-host disease
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100041&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100041&lng=en&tlng=en

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